Paulo Carvalho
Assistant Professor - Pharmaceutical Sciences, School of Pharmacy
Office: Bunting 205
To schedule an appointment and/or general information, please contact:
Department of Pharmaceutical Sciences
410-532-5206
Education
Ph.D. Medicinal Chemistry - Universidade de Sao Paulo, USP, Sao Paulo, Brazil, 2001
M.Sc. Medicinal Chemistry - Universidade de Sao Paulo, USP, Sao Paulo, Brazil, 1997
Doctor of Pharmacy - Universidade de Sao Paulo, USP, Sao Paulo, Brazil, 1989
Research Interests
Bioactive Natural Products, Synthesis and biological evaluation of drugs against tropical diseases, Synthesis and biological evaluation of anticancer drugs, Analytical methods for identification of new chemical entities and quantification of drugs in biological fluids.
Publications
Jain, S., Abraham, I., Carvalho, P. et.al. Sipholane Triterpenoids: Chemistry, Reversal of ABCB1/P-Glycoprotein-Mediated Multidrug Resistance, and Pharmacophore Modeling. J. Nat. Prod. (2009), 72, 1291–1298
Chittiboyina, A.G., Gundluru, M.K., Carvalho, P.B. et. al. Total Synthesis and Absolute Configuration of Laurenditerpenol: A Hypoxia Inducible Factor-1 Activation Inhibitor. J. Med. Chem. (2008), 50, 6299 – 6302.
Li, Z., Watkins, E. B., Liu, H., Chittiboyina, A. G., Carvalho, P. B., and Avery, M. A. 1,3-Diaxially Substituted trans-Decalins: Potential Nonsteroidal Human Progesterone Receptor Inhibitors. J. Org. Chem. (2008), 73(19); 7764-7767.
Gul, W., Carvalho, P. et. al. (6aR,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-yl-4-methylbenzenesulfonate Acta Cryst. (2008). E64, o1686
Ali, Z., Ferreira, D., Carvalho, P., Avery, M. A., and Khan, I. A. Nigellidine-4-O-sulfite, the First Sulfated Indazole-Type Alkaloid from the Seeds of Nigella sativa. J. Nat. Prod.; (2008), 71(6); 1111-1112.
Carvalho, P. B., Bikbulatov, R., Zjawiony, J. K., and Avery, M. A.. Unusual hemi-acetal structure derived from Salvinorin A. Acta Cryst. (2008). E64, o1370-o1371.
Professional Affiliations & Memberships
American Chemical Society
American Association of Pharmaceutical Scientists
Canadian Society for Pharmaceutical Sciences,
Sigma Xi
The Scientific Research Society